Some genes have mutations or mistakes, which means that they do not perform properly. Such mutations are very common; in fact, just about everyone has some form of abnormal genes. Although most mutations are harmless, some can increase your risk of developing certain diseases, such as breast cancer. Mutations can either be inherited or occur during the course of a person's lifetime.
In the past few years, research has indicated the presence of a specific gene mutation in families with a history of breast cancer. These abnormalities are often found in genes named BRCA1 and BRCA2 (BReast CAncer gene 1 and BReast CAncer gene 2). While the normal version of these genes do not harm its carrier, the abnormal BRCA1 and BRCA2 genes are associated with higher rates of breast and/or ovarian cancer. BRCA1 and BRCA2 abnormalities are linked to about 5% to 10% of breast cancers. |
